Superresolution Microscopy
Exceptional Precision for Demanding Tasks
Superresolution microscopy requires precise, reliable, and reproducible sample positioning, objective alignment, and imaging system integration. With its advanced piezo-driven technology, PI’s ultrasound-based microscope platform offers exceptional precision, making it the perfect choice for demanding tasks in modern microscopy.
The platform is designed for a broad range of applications, including widefield and confocal fluorescence microscopy, deep tissue fluorescence imaging, multi-photon techniques, and superresolution microscopy. To optimally support all applications, the platform can be expanded with specialized components such as subnanometer resolution XYZ stages, piezo scanning Z stages, and holders for slides, Petri dishes, and microtiter plates. When combined with a piezo-controlled focus scanner, the system delivers exceptional linearity, stability, and maintenance-free operation. Additionally, its mechanical compatibility with leading manufacturers’ microscopes ensures versatility, while innovative technology makes this high-precision positioning solution accessible to a broad spectrum of users.
Key Features
XY Axis - Precise Sample Positioning Stage
- Exceptional stability and minimal long-term drift
- High-resolution PILine® piezo linear drives for precise motion, small minimum step size, and good reproducibility
- Dual-frequency drive mode for smooth operation and minimized noise
- Automatic trajectory parameter adaptation to ensure maximum stability and reproducibility
- SW-compatibility: µManager, NIKON NIS Elements, Python, Andor iQ, NI LabVIEW
- User-friendly PI software: PIMikroMove®, PI General Command Set (GCS)
>> U-781 PILine® XY Stage System
XY(Z) Axis - Nanometer Sample Positioning Stage
- Subnanometer resolution with millisecond response times
- Precision positioning of +/- 5 nm
- Low-profile construction (20 mm) for seamless integration
- Clear aperture compatible with 3×1" microscope slides; recessed, insertable holder included in scope of delivery
- Travel ranges up to 200 µm × 200 µm × 200 µm
- Exceptional durability with PICMA® piezo actuators
>> P-545.xR8S PInano® XY(Z) Piezo System
Z Axis - Fine Positioning of Microscope Objectives Drive
- World famous PIFOC® series (PIFOC = PI Focus Drive)
- Mechanically compatible with standardized objective nosepiece threads
- Subnanometer precision for fine positioning of objectives
- Large clear aperture with Ø 29 mm for improved optical performance
- Faster response and longer lifespan compared to motorized drives
- Travel range options: 100 µm, 400 µm, and 800 µm
>> P-725.xCDE1S PIFOC®
Motion Control
- Most systems include a controller, whereas some offer optional controllers with varying levels of precision
- Trajectory support for 1D or 2D motion patterns
- Integrated interfaces: USB, RS-232, TCP/IP, SPI, I/O
- Integrated power amplifier with dynamic frequency control for stable performance
- Multifunctional encoder input: A/B, sin/cos, BiSS for versatile connectivity
- Macro programmable for stand-alone operation
- Daisy chain networking support for scalable configurations
>> Motion Controller
